Dactinomycin 0.5 mg

Dactinomycin is an antineoplastic (anti-cancer) chemotherapy drug used to treat specific types of cancer. It belongs to the antitumor antibiotic class and works by inhibiting DNA synthesis and preventing the growth and division of cancer cells.

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Indications for Use:

Used as part of chemotherapy protocols for:

• Wilms’ Tumor in children

• Choriocarcinoma

• Ewing’s Sarcoma

• Rhabdomyosarcoma

• Adjuvant or palliative therapy for certain solid tumors

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Warnings & Precautions:

• Administered only under specialist oncologist supervision.

• May cause bone marrow suppression.

• High risk of nausea and vomiting.

• Possible hair loss.

• Risk of hepatic and renal toxicity.

• Contraindicated during pregnancy.

• Regular monitoring of liver, kidney functions, and blood counts is essential.

• Avoid extravasation (leakage outside the vein) as it can cause severe tissue damage.

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Composition:

Each vial contains:

• Dactinomycin 0.5 mg

Other ingredients:

• Preservatives as per manufacturer

• Sterile water for injection

(Reconstituted with a suitable solvent before administration)

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Dosage & Administration:

• Administered by intravenous injection (IV) only.

• Dosage is individualized based on tumor type, patient weight, and body surface area.

• Usually given as part of a combined chemotherapy regimen.