Endoxan Injection

Endoxan is an antineoplastic and immunosuppressive agent containing Cyclophosphamide. It belongs to the alkylating agents class, which work by interfering with the DNA replication of cancer cells, inhibiting their growth and division.
It’s administered intravenously for treating various cancers and certain autoimmune conditions.

Indications for Use:

• Breast cancer

• Ovarian cancer

• Hodgkin’s and Non-Hodgkin’s lymphoma

• Leukemia

• Neuroblastoma

• Multiple myeloma

• Autoimmune diseases (e.g., Systemic Lupus Erythematosus, Vasculitis)

Warnings & Precautions:

• Regular blood counts are essential during therapy.

• Contraindicated in patients allergic to Cyclophosphamide.

• Use with caution in patients with liver or kidney impairment.

• May cause immunosuppression, increasing infection risk.

• Potential side effects: nausea, vomiting, hair loss, hemorrhagic cystitis (blood in urine), bone marrow suppression.

• Pregnancy must be avoided during and for a specified period after treatment.

• Adequate hydration is recommended during treatment to prevent bladder toxicity.

Composition:

Each vial contains:

• Cyclophosphamide — depending on the pack strength (commonly 200 mg, 500 mg, 1 g)

Dosage & Administration:

• Administered intravenously via slow injection or infusion, according to the patient’s condition, body weight, and doctor’s prescription.

• Should be prepared under aseptic conditions, ensuring safe handling and disposal.